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1

In vitro metabolism of 10-(3-chlorophenyl)-6,8,9,10-tetrahydrobenzo[b][1,8]naphthyridin-5(7H)-one, a topical antipsoriatic agent. Use of precision-cut rat, dog, monkey and human liver slices, and chemical synthesis of metabolites

Shmuel Zbaida, Yancy Du, Daniel Shannon, Donald Laudicina, C. Mohan Thonoor, Kwokei Ng, Neil Blumenkrantz, James E. Patrick, Mitchell N. Cayen, Richard Friary, Vera Seidl, Tze-Ming Chan, Birendra Pram

Journal:

Biopharmaceutics & Drug Disposition

Year:

1998

Language:

english

File:

PDF, 405 KB

english, 1998

2

Enantiomerization of an atropisomeric drug

Richard J. Friary, Michael Spangler, Rebecca Osterman, Lara Schulman, John H. Schwerdt

Journal:

Year:

1996

Language:

english

File:

PDF, 696 KB

english, 1996

3

Transfer hydrogenolysis: an improved synthesis of (R)-(-)-α-Methyl Histamine

Richard J. Friary, Pietro Mangiaracina, Mehdi Nafissi, Steven C. Orlando, Stanley Rosenhouse, Vera A. Seidl, Neng-Yang Shih

Journal:

Year:

1993

Language:

english

File:

PDF, 293 KB

english, 1993

4

Intramolecular transaminations of enaminones: a synthesis of fused, polycyclic, N-aryl pyridones

Richard J. Friary, Vera Seidl, John H. Schwerdt, Marvin P. Cohen, Donald Hou, Mehdi Nafissi

Journal:

Year:

1993

Language:

english

File:

PDF, 786 KB

english, 1993

5

Intermolecular transaminations of enaminones: a synthesis of fused, polycyclic, N-aryl pyridones

Richard J. Friary, Vera Seidl, John H. Schwerdt, Tze-Ming Chan, Marvin P. Cohen, Edward R. Conklin, Timothy Duelfer, Donald Hou, Mehdi Nafissi, Robert L. Runkle, Pirouz Tahbaz, Robert L. Tiberi, Andre

Journal:

Year:

1993

Language:

english

File:

PDF, 1.20 MB

english, 1993

6

Oxidative cleavage of a tricyclic pyridone to a bicyclic lactam-dione

Richard J. Friary, John H. Schwerdt

Journal:

Year:

1991

Language:

english

File:

PDF, 289 KB

english, 1991

7

Synthesis and topical antiinflammatory activity of some steroidal [16.alpha.,17.alpha.-d]-isoxazolidines

Green, Michael J., Tiberi, Robert L., Friary, Richard, Lutsky, Barry N., Berkenkoph, Joseph, Fernandez, Xiomara, Monahan, Margaret

Journal:

Journal of Medicinal Chemistry

Year:

1982

Language:

english

File:

PDF, 612 KB

english, 1982

8

Heterocyclic synthesis via the intramolecular acylation of enamines derived from amino acids

Friary, Richard J., Gilligan, Jeanne M., Szajewski, Richard P., Falci, Kenneth J., Franck, Richard W.

Journal:

Journal of Organic Chemistry

Year:

1973

Language:

english

File:

PDF, 681 KB

english, 1973

9

Synthesis of podocarpic acid

Spencer, Thomas A., Friary, Richard J., Schmiegel, Walter W., Simeone, Joseph F., Watt, David S.

Journal:

Journal of Organic Chemistry

Year:

1968

Language:

english

File:

PDF, 1.14 MB

english, 1968

10

Total synthesis of racemic methyl vinhaticoate

Spencer, Thomas A., Villarica, Rodolfo M., Storm, David L., Weaver, Thomas D., Friary, Richard J., Posler, Jeanette., Shafer, Paul R.

Journal:

Journal of the American Chemical Society

Year:

1967

Language:

english

File:

PDF, 373 KB

english, 1967

11

Syntheses of methyl deisopropyldehydroabietate. Diterpenoid synthesis by the AB.fwdarw.ABC approach

Spencer, Thomas A., Weaver, Thomas D., Villarica, Rodolfo M., Friary, Richard J., Posler, Jeanette, Schwartz, Martin Alan

Journal:

Journal of Organic Chemistry

Year:

1968

Language:

english

File:

PDF, 1.17 MB

english, 1968

12

Correction. Synthesis of Methyl Deisopropyldehydroabietate. Diterpenoid Synthesis by the AB → ABC Approach.

Spencer, Thomas, Weaver, Thomas, Villarica, Radolfo, Friary, Richard, Posler, Jenette, Schwartz, Martin

Journal:

Journal of Organic Chemistry

Year:

1968

Language:

english

File:

PDF, 144 KB

english, 1968

13

The intramolecular acylation of enamine-acids

Friary, Richard J., Franck, Richard W., Tobin, Joseph F.

Journal:

Journal of the Chemical Society D Chemical Communications

Year:

1970

Language:

english

File:

PDF, 150 KB

english, 1970

14

Alleged alkylations of ?-hydroxyimines to betaines: revisions of the structure of educts and products

Friary, Richard, Kirby, Gordon W.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1984

Language:

english

File:

PDF, 127 KB

english, 1984

15

Job$ in the Drug Indu$try || Preface

Friary, Richard

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

16

Job$ in the Drug Indu$try || Qualifying and Searching for Jobs in the Drug Industry

Friary, Richard

Year:

2000

Language:

english

File:

PDF, 1.76 MB

english, 2000

17

Job$ in the Drug Indu$try || Evaluating Companies and Job Offers

Friary, Richard

Year:

2000

Language:

english

File:

PDF, 1.89 MB

english, 2000

18

Novel Syntheses of Tricyclic, N-Aryl, Pyridine- and Pyrazine-Fused Pyrimidones

Friary, Richard, McPhail, Andrew T., Seidl, Vera

Journal:

Collection of Czechoslovak Chemical Communications

Year:

1993

File:

PDF, 1.28 MB

1993

19

Job$ in the Drug Indu$try || Discovery Research

Friary, Richard

Year:

2000

Language:

english

File:

PDF, 2.48 MB

english, 2000

20

Job$ in the Drug Indu$try || Chemical Development

Friary, Richard

Year:

2000

Language:

english

File:

PDF, 1.79 MB

english, 2000

21

Job$ in the Drug Indu$try || Enticements

Friary, Richard

Year:

2000

Language:

english

File:

PDF, 2.49 MB

english, 2000

22

Job$ in the Drug Indu$try || Jobs in the Drug Industry

Friary, Richard

Year:

2000

Language:

english

File:

PDF, 1.57 MB

english, 2000

23

Job$ in the Drug Indu$try || Elements of Drug Discovery and Development

Friary, Richard

Year:

2000

Language:

english

File:

PDF, 1.78 MB

english, 2000

24

Job$ in the Drug Indu$try || Discovery Research

Friary, Richard

Year:

2000

File:

PDF, 2.48 MB

2000

25

Job$ in the Drug Indu$try || Jobs in the Drug Industry

Friary, Richard

Year:

2000

File:

PDF, 1.57 MB

2000

26

Job$ in the Drug Indu$try || Chemical Development

Friary, Richard

Year:

2000

File:

PDF, 1.79 MB

2000

27

Job$ in the Drug Indu$try || Elements of Drug Discovery and Development

Friary, Richard

Year:

2000

File:

PDF, 1.78 MB

2000

28

Job$ in the Drug Indu$try || Enticements

Friary, Richard

Year:

2000

File:

PDF, 2.49 MB

2000